Gem of Efficacious Toxin

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Rank 6, seen on the early PTR testing.

Gem of Efficacious Toxin is a Legendary Gem findable only from Greater Rift Guardians in Reaper of Souls.

Legendary gems can only be socketed in rings and amulets worn by a character (not by a Follower) and provide dramatic and powerful bonuses that are huge upgrades over any normal gems in the game.

All legendary gems improve with upgrades to rank 50, which can only be obtained via the NPC Urshi who appears after the death of a Guardian of a Greater Rift that is not completed in time.


Gem Properties[edit]

Gem of Efficacious Toxin

  • Poison all enemies hit for 1000% weapon damage over 10 seconds.
  • Upgrade rank grants: +20% weapon damage over 10 seconds.


Rank 25 unlocks:

  • All enemies you poison take 10% increased damage from all sources.

The poison mixers of Xiansai tell of a sickly gem cutter
named Zhong Yi Rou who would come by their vats and scream "I'll
put you all out of work someday! Yes I will!"

Stats at Higher Ranks[edit]

All Legendary Gems improve from rank 1 up to rank 50, with additional stats for the primary bonus, and the extra bonus property unlocking at the maximum upgrade rank of 50.

Stats are pulled from the PTR and may differ in the final game.

  • Rank 1: Poison all enemies hit for 1000% weapon damage over 10 seconds.
  • Rank 2: Poison all enemies hit for 1020% weapon damage over 10 seconds.
  • Rank 3: Poison all enemies hit for 1040% weapon damage over 10 seconds.
  • Rank 4: Poison all enemies hit for 1060% weapon damage over 10 seconds.
  • Rank 5: Poison all enemies hit for 1080% weapon damage over 10 seconds.
  • Rank 10: Poison all enemies hit for 1180% weapon damage over 10 seconds.
  • Rank 15: Poison all enemies hit for 1280% weapon damage over 10 seconds.
  • Rank 20: Poison all enemies hit for 1380% weapon damage over 10 seconds.
  • Rank 25: Poison all enemies hit for 1480% weapon damage over 10 seconds.
  • Rank 30: Poison all enemies hit for 1580% weapon damage over 10 seconds.
  • Rank 35: Poison all enemies hit for 1680% weapon damage over 10 seconds.
  • Rank 40: Poison all enemies hit for 1780% weapon damage over 10 seconds.
  • Rank 45: Poison all enemies hit for 1880% weapon damage over 10 seconds.
  • Rank 50: Poison all enemies hit for 1980% weapon damage over 10 seconds.


Gallery[edit]