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The Devil's Fang is a special quest item that is required for as part of the [[Infernal Machine]] eventin Diablo 3 classic. This item can not be found in Reaper of Souls, though old D3v Writhing Spines can be used in RoS, but only to obtain the organs to craft the D3v version of the [[Hellfire Ring]].

The Devil's Fang is a special item required for the [[Infernal Machine]] event. It can only be obtained in the [[Realm of Chaos]], a special quest area. There players will face uber versions of [[Ghom]] and [[Rakanoth]] one of whom may drop the [[Devil's Fang]].

Note that steps 1-3 must be repeated multiple times, since you must create at least three red portals to obtain all three demonic organs. Furthermore, unless you are playing on Monster Power 10, the keywardens do not always drop keys and the uber bosses do not always drop the demonic organs.